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ACE-031 Peptide

$150.00

For Research Use Only. Not for human use. Research-grade ACE-031 (ActRIIB-Fc fusion protein), a soluble decoy receptor comprising the activin type IIB receptor extracellular domain fused to IgG1-Fc, intended for controlled laboratory investigations of myostatin/activin A signaling blockade and neuromuscular pathway research.

SKU: ace-031 Category: Tags: , ,

Discount per Quantity

Quantity 5 – 9 10 +
Discount 5% 10%
Price $142.50 $135.00

Orders over $200: FREE USPS Priority shipping.

  • >99% purity — HPLC + MS verified
  • Cold-pack insulated mailers
  • Discreet US shipping (2–5 days)
  • COA available on request

Research Use Only. Not for human consumption. Sold strictly for laboratory and research use.

For Research Use Only. Not for human use.

ACE-031 is a recombinant fusion protein originally developed as a clinical candidate. It functions as a soluble decoy receptor comprising the extracellular domain of the activin type IIB receptor (ActRIIB) fused to an IgG1-Fc region. It binds myostatin (GDF-8), activin A, and related TGF-β family ligands with high affinity, competitively inhibiting their interaction with endogenous ActRIIB receptors. This research-grade lyophilized protein is produced under strict quality controls and is provided with full analytical documentation for use in laboratory research settings.

Key Scientific Attributes

  • High-purity ACE-031 (≥98% by HPLC/SEC, recombinant human sequence)
  • Verified ActRIIB extracellular domain + IgG1-Fc fusion with correct disulfide bonding
  • Lyophilized formulation for long-term stability under appropriate laboratory storage conditions
  • Full Certificate of Analysis (COA) with HPLC, SEC, binding ELISA (myostatin/activin A), and endotoxin testing
  • Manufactured in GMP-aligned, ISO-compliant facilities
  • Suitable for in vitro myostatin/activin A blockade studies and neuromuscular pathway research models

Research-Referenced Attributes

  • Potent myostatin/activin A sequestration activity as characterized in peer-reviewed scientific literature
  • Mechanistic data available in published preclinical and clinical-phase research literature
  • Well-characterized biochemical profile based on published human trial documentation
  • Relevant to research areas including sarcopenia biology, cachexia mechanisms, and neuromuscular disease models (e.g., DMD)

Why Researchers Choose Nationwide Peptides ACE-031

  • Sequence-verified match to the clinically studied ActRIIB-Fc construct
  • High documented myostatin-binding affinity as confirmed by functional binding ELISA
  • Transparent analytical data (HPLC/SEC >98%)
  • Suitable for muscle physiology, neuromuscular disease, and regenerative biology laboratory investigations
  • Competitive research pricing with bulk options available

This product is intended for laboratory and research use only. It is not intended for human or animal consumption, and is not a drug, supplement, or therapeutic product.

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