PT-141 – Bremelanotide Peptide

PT-141 (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH) is a cyclic, lactam-bridged analog of α-melanocyte-stimulating hormone (α-MSH) originally developed as a tanning peptide. It acts centrally via activation of the melanocortin-4 receptor (MC4R) in the hypothalamus. As noted in the peer-reviewed literature, bremelanotide is a melanocortin receptor agonist of interest for the study of central melanocortin signaling pathways (sciencedirect.com). This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation. For Research Use Only. Not for human use.

Key Scientific Attributes

• High-purity PT-141 (≥ 98% by HPLC/MS, acetate salt form)
• Verified cyclic heptapeptide sequence with lactam bridge (Asp-Lys)
• Lyophilized formulation for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
• Manufactured in GMP-aligned, ISO-compliant facilities
• Suitable for MC4R signaling and central melanocortin pathway research

Research-Referenced Attributes (Based on scientific literature; not therapeutic claims.)

• Selective agonist activity at melanocortin receptors MC3R and MC4R, which are expressed primarily in the central nervous system.
• Cyclic heptapeptide structure derived from α-MSH, studied for central nervous system receptor binding interactions
• Subject of published in-vivo and in-vitro melanocortin receptor binding studies
• Molecular formula C50H68N14O10; Molecular Weight: 1025.16 g/mol (ichemical.com)

Why Researchers Choose PT-141

• Sequence-verified Bremelanotide analog for reproducible laboratory research
• Transparent analytical data (HPLC >98%, MS confirmation of cyclic structure)
• Trusted by neuroendocrinology and pharmacology laboratories
• Competitive research pricing with bulk options

For Research Use Only. Not for human use.