SS-31 (Elamipretide) Peptide

For Research Use Only. Not for Human Use.

SS-31 (Elamipretide) is a water-soluble, cell-permeable mitochondria-targeting tetrapeptide. It selectively concentrates >1,000-fold in the inner mitochondrial membrane, where it interacts with cardiolipin to stabilize cristae architecture, support electron transport chain function, and inhibit cytochrome c release in experimental models. This research-grade lyophilized peptide is synthesized under strict quality controls and provided with full analytical documentation, making it a widely referenced tool in laboratory investigations of mitochondrial biology.

Key Scientific Features

• High-purity SS-31 (≥99% by HPLC/MS, TFA salt form)
• Verified aromatic-cationic sequence: D-Arg-2′,6′-dimethyl-Tyr-Lys-Phe-NH₂
• Lyophilized formulation for maximum long-term stability
• Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
• Manufactured in GMP-aligned, ISO-compliant facilities
• Suitable for cardiolipin interaction, mitochondrial ROS, and bioenergetics in vitro studies

Research-Referenced Attributes (Based on published scientific literature; not therapeutic claims.)

• Concentrates >1,000-fold in mitochondria — interacts with cardiolipin and ETC supercomplexes in experimental systems
• Observed to modulate mitochondrial ROS and mPTP dynamics in in vitro and preclinical models
• Subject of published preclinical studies examining mitochondrial function in ischemia-reperfusion, neurodegenerative, and skeletal muscle in vitro models
• Exact clinical-sequence match to Elamipretide as described in peer-reviewed literature

Why Researchers Choose Nationwide Peptides SS-31

• Sequence fidelity to published Elamipretide reference standard
• Transparent analytical data (HPLC >99%, MS confirmation)
• Trusted by mitochondrial biology, cardiology, and neuroscience research laboratories
• Competitive research pricing with bulk options available